Over the recent years, there has been excitement about the extraordinary oppor- tunities that artificial intelligence may offer in tomorrow’s healthcare. Given the potential of AI technology in facilitating the quantification of large and complex datasets, medical imaging has witnessed rapid and revolutionary developments. However, a limitation of current AI developments for medical imaging is that they have overwhelmingly, and almost entirely, targeted imaging applications in high- income settings. Hence, it is important to promote and accelerate the development of trustworthy and accessible AI solutions for medical imaging in low-to-middle income countries –an urging need to advance global healthcare. This paper de- scribes the authors’ experience and initiatives in promoting AI for medical imag- ing on the African continent, by Africans for Africans. First, the paper will discuss MICCAI 2024, the first international conference on medical image computing and computer assisted intervention that will be taking place on the continent. Subse- quently, we will present AFRICAI, a new African network dedicated to research, education and cooperation in the field of AI in imaging and radiology. With this paper, we hope to raise awareness about these initiatives and attract more collabo- rators, promote new research and innovation in the field to address Africa-specific healthcare challenges, and encourage similar initiatives for promoting practical AI solutions for developing countries in Africa and beyond.